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Health

السرطان.. مركب نباتي يضعف مقاومة الأورام

By روسيا اليوم · 3 hours ago · 1 min read روسيا اليوم ↗

السرطان.. مركب نباتي يضعف مقاومة الأورام

ما يعرفه ريفو عن الخبر

كشف باحثون في مركز جونس هوبكنز أن مركب تريبتوليد المستخلص من نبات ثلاثية الجنيحات ويلفوردي يعطل إنزيما يعيق فعالية أدوية السرطان.
يعمل مركب تريبتوليد على تعطيل إنزيم DCTPP1 الذي تستخدمه الخلايا السرطانية لتدمير مثبطات إنزيم ميثيل ترانسفيراز الحمض النووي.
أظهر دمج مركب تريبتوليد مع عقار ديسيتابين تعزيز قدرة العلاج على تنشيط الجينات الكابتة للأورام وقتل الخلايا السرطانية في النماذج المخبرية.
يساهم هذا الاكتشاف في التغلب على العقبات التي تحد من فعالية الأدوية ضد الأورام الصلبة التي تمتلك آليات دفاعية.

في ظل تزايد مقاومة بعض الأورام لعلاجات السرطان، تتجه الأبحاث إلى مركبات طبيعية قد تساعد في إضعاف هذه المقاومة وتعزيز فعالية العلاجات المتاحة.

المصدر: روسيا اليوم

#روسيا

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