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Science & Tech

بقايا فيروسات قديمة في جينوم الإنسان تتنبأ بالاستجابة للعلاج الكيميائي

By الشرق الأوسط · 5 hours ago · 1 min read الشرق الأوسط ↗

بقايا فيروسات قديمة في جينوم الإنسان تتنبأ بالاستجابة للعلاج الكيميائي

ملخص الخبر

كشفت دراسة أن بقايا فيروسات قديمة في الجينوم البشري ترتبط بضعف استجابة مرضى سرطان الدم للعلاج الكيميائي.
ساهم دمج بيانات هذه الفيروسات في نماذج الذكاء الاصطناعي في تحسين القدرة على التنبؤ بالمرضى الذين يعانون من مقاومة العلاج.
توجد هذه البقايا في أجزاء غير مشفرة من الجينوم وتسمى بالجينوم المظلم وقد تؤثر على العمليات البيولوجية والإشارات المناعية.
تساعد هذه النتائج في تطوير استراتيجيات علاجية أكثر تخصيصاً لمرضى سرطان الدم النقوي الحاد عبر استغلال معلومات الجينوم المظلم.

ملخص كتبه الذكاء الاصطناعي من نص الخبر في مصدره.

أجزاء منها أصابت أسلاف الإنسان قبل ملايين السنين ثم اندمجت في المادة الوراثية

المصدر: الشرق الأوسط

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